1. Brief biography of author
Name: Michiyuki Matsuzaki DOB: June 26, 1950
March 1975 M.D.(provisional), School of Medicine, Hokkaido University
April 1975 Internship and Residency, Internal Medicine 1, Graduate School of Medicine, Hokkaido University
June 1986 Executive Board Member of Hokkaido Physicians and Dentists Against Nuclear War
September 1986 Doctoral thesis for M.D. accepted, School of Medicine, Hokkaido University
April 2010 Head of Internal Medicine Department, Fukagawa Municipal Hospital, Hokkaido
April 2012 Professor of Clinical Administration, Asahikawa Medical University, Hokkaido
May 2012 Special member of Cancer Policy Board, Hokkaido Prefecture
2. Thyroid Disorders
(1) Thyroid cysts found in 35% of Fukushima children examined with an average age of 10.
Thyroid examinations of Fukushima children have been
implemented as part of the “Fukushima Prefecture Health Management
Survey” to monitor the health effects of the Fukushima Daiichi Nuclear
Power Plant nuclear accident. The results of the thyroid examinations
released on April 26, 2012 are summarized here.
【The official document in Japanese may be downloaded from the following link.】
The implementation status of the examinations and the
summary of the results are shown in the above document, the sixth report
of Fukushima Prefecture Health Management Survey.
(Translator note: As of the date of translation in
late July, 2012, the seventh report was available, which covered further
analysis of the same data from the sixth report. For a complete
description of the thyroid examination and analysis of data from both
reports in English, please refer to this article. http://fukushimavoice-eng.blogspot.com/2012/07/thyroid-examination-by-fukushima.html)
Age distribution of the children who received thyroid examinations (average age of 10 in 4th or 5th grades), follow.
Ages 0-5: 9,826 children
Ages 6-10: 10,662 children
Ages 11-15: 11,466 children
Ages 16-18: 6,160 children
In regards to Fukushima thyroid examinations including
children from babies and infants up to high school students, I would
like to discuss the prevalence of “cysts” detected by thyroid ultrasound
examinations in comparison to the research result reported in the past.
(2) In 250 children ages 7 to 14, two children (0.8%) had thyroid cysts.
(Based on a study co-authored by Shunichi Yamashita)
【This paper may be downloaded from the following link】
Nagasaki University’s study in 2006, co-authored by the current Fukushima University Medical School vice president Shunichi Yamashita, examined 250 children in Nagasaki prefecture with ultrasound. Two children (0.8%) were found to have thyroid cysts. (Cited in second paragraph on page 593 of the above study.)
(3) There are few incidences of thyroid nodules or
cysts at birth. Thyroid abnormalities begin to gradually increase past
age 5. By age 20, one in ten has thyroid nodules and/or cysts. (Study
by Mazafferri in New England Journal of Medicine.)
The study published in 1993 (Mazzarerri EL, et al. Management of a solitary thyroid nodule. N Engl J Med
1993 Feb 25;328(8):553-9.) examined mostly Americans with ultrasound
examinations and autopsy/biopsy. The study revealed that few thyroid
“nodules” (The study defined both tumors and cysts as nodules.) were
found at birth. Incidence began to gradually increase past the age of
five, proportionate with age, with one in ten having thyroid nodules
and/or cysts by age 20. (The graph below has been compiled from Figure 1
in this study: ● represents the prevalence of thyroid nodules detected
at autopsy or by ultrasound. □ represents the prevalence of thyroid
nodules detected by palpation.) In addition, the study stated that
25-35% of the “nodules” were “cysts.’
Prevalence of Palpable Thyroid Nodules Detected at
Autopsy or by Ultrasound (●) or by Palpation (□) in Subjects without
Radiation Exposure or Known Thyroid Disease.
The above graph indicates that the prevalence of
thyroid nodules in children around the age of ten is about 1-2%. Since
25-35% of them turned out to be cysts, the prevalence of thyroid cysts
is estimated to be about 0.5-1%.
(4) Prevalence of thyroid cysts in Chernobyl children under the age of 18 was 0.5%.
(The Nippon Foundation study)
【The above article may be downloaded from the following link】
From 5 to 10 years after the Chernobyl accident, Shunichi Yamashita, the vice president of Fukushima University Medical School, conducted ultrasound thyroid examinations in a total of 160,000 children in Gomel and surrounding areas with marked radioactive contamination. In this study, “nodules” and “cysts” were recorded separately: “nodules” mean solid tumors. The results show that cysts were seen in 0.5% and also “nodules (solid tumors)” were seen in 0.5%. Below is Figure 11 from this study, seen in above URL.
Figure 11. Dynamics of prevalence of abnormal findings by thyroid ultrasound examinations (1991-1996).
(5) Prevalence of thyroid “cysts” in Fukushima children is higher than in any other studies.
When the above four studies are tallied in one table,
it becomes obvious that the result of the thyroid examinations of
children in the “Fukushima Prefecture Health Management Survey” is
astonishing. This is because one-third of the children had developed “
cysts.” A “cyst” is a fluid-filled sac. Cysts don’t mean there is an
immediate chance of developing thyroid cancer. However, it is apparent
that something extraordinary is happening inside the thyroid gland, such
as inflammation or changes in cellular properties.
Subject description
|
History of accidental radiation exposure
|
Prevalence of thyroid cysts
|
Fukushima children ages 0-18 (average age 10)
|
Yes
|
35 %
|
Nagasaki children ages 7-14
|
No
|
0.8 %
|
American children age 10
|
No
|
0.5-1 %
|
Chernobyl children under age 18
|
Yes
|
0.5 %
|
【Section 2 Summary】
- Summarizing the thyroid ultrasound examination results from Japan and overseas, prevalence of “cysts” detected in children around the age of 10 is approximately 0.5-1.0%.
- The fact that 35% of Fukushima children (average age around 10) have thyroid cysts strongly suggests that these children’s thyroid glands are negatively affected by undesirable environmental factors.
- There is a strong concern that waiting for further analysis of above data and the completion of follow-up examinations will lead to irreversible health damages in these children.
- Consequently, it is strongly desired that small children living in Nakadori (adjacent to the coastal region) and Hamadori (the coastal region) in Fukushima receive immediate implementation of preventive measures such as evacuation and more frequent screening examinations.
- Based on above findings, a letter from Shunichi Yamashita to thyroid specialists all over Japan, instructing them not to offer second opinions to concerned families, can only be considered a repressive conduct: a violation of human rights for those exposed to radiation and current patients.
3. Pulmonary Function
Sevendsen et al, from the Department of Epidemiology
and Biostatistics, University of South Carolina, demonstrated in 2010
that children who had been living in areas heavily contaminated with
radioactive cesium have decreased pulmonary function.
【This article may be downloaded from the following link】
Svendsen et al. 137Cesium Exposure and Spirometry Measures in Ukrainian Children Affected by the Chernobyl Nuclear Incident. Environmental Health Perspectives 2010 May;118(5): 720-725.
In this study, pulmonary function of 415 children under
the age of 18 (mode age 8-9) was followed from 1993 to 1998. The
result showed that children who continuously lived in areas with the
highest Cs-137 soil contamination (average 355 kBq/㎡) had 4-5% less
forced expiratory volume in 1 sec (FEV1) than children who continuously lived in areas with the lowest soil contamination (average 90 kBq/㎡).
Forced expiratory volume per 1 sec (FEV1)
is the portion of the forced vital capacity exhaled in the first second
of forced exhalation. Elementary school children can normally exhale
over 3 liters in the first second of forced exhalation. A decrease of
4-5 % FEV1 means a decrease of 100 -150 cc of absolute volume of exhaled air.
Normally pulmonary function peaks around age 20, and from then on, FEV1 decreases by 20-30 cc per year.
A decrease of FEV1 by 150cc means either an early aging of lungs or a failure of pulmonary maturity by 5-7 years.
Children who continuously live in areas of Ukraine with
355 kBq/㎡ soil contamination will have pulmonary function aging five
years faster than those living in uncontaminated areas.
Currently in Fukushima, which areas have Cs-137 levels of 355 kBq/㎡ vs. 90 kBq/㎡?
This is a soil contamination distribution map created by the Ministry of Education, Culture, Sports, Science and Technology last year and depicts the total soil concentration of Cs-134 and Cs-137(Bq/m2) calculated to the value estimated for August 28, 2011.
Deep blue ■
indicates a soil contamination level of 60-100 kBq/㎡, framing the
hillsides of Nakadori: this is comparable to the “low contamination
area” in the Sevedsen study.
Light blue ■
indicates a soil contamination level of 300-600 kBq/㎡, comparable to
the highest contaminated areas in Ukraine. All areas in Nakadori, such
as Fukushima-city and Koriyama-city, have contamination levels somewhere
between “low” and “the highest.”
Therefore, children currently living in Hamadori
(coastal region) and Nakadori (adjacent to the coastal region) are at
risk of accelerated pulmonary aging by several years.
Furthermore, this study underestimates the effect of radiation exposure by using the control group in low contamination areas in comparison. We must therefore be prepared to face much greater health damage in reality.
4. Bone Marrow Function
The next study to be presented exhibits data about
hematopoietic dysfunction due to radiation exposure in children who kept
living in highly contaminated areas leading to leukopenia and anemia.
This is a 2008 study published in Environmental Health by Dr. Stepanova
from Scientific Center for Radiation Medicine, Academy of Medical
Sciences of Ukraine. It’s a follow-up study of blood counts in 1,251
children living in Narodichesky region, Zhitomir Oblast, Ukraine from 7
to 11 years after the accident.
【This article may be downloaded from the following link】
Stepanova et al. Exposure from the Chernobyl accident
had adverse effects on erythrocytes, leukocytes, and, platelets in
children in the Narodichesky region, Ukraine: A 6-year follow-up study. Environ Health. 2008; 7: 21-.
The study revealed that children living in high
contamination areas (350-879 kBq/㎡) had a 20% less leukocyte count
(5,810 vs. 6,870) than those living in low contamination areas (29-112
kBq/㎡). Platelet count and erythrocyte count were also less by 5-10%.
Currently in Fukushima, areas around Nakadori indicated in deep blue ■ in the previous map is similar to low contamination areas and Kawamata-machi (outside edge of Iitate-mura) area in green ■ is similar to high contamination areas.
Therefore, what we need to medically assume from this study is that there
is a possibility that hematopoietic function of the bone marrow might
be suppressed for a long time in children who are currently living in
Hamadori and Nakadori of Fukushima. Leukopenia reduces body’s
resistance against bacteria and viruses. Low red blood cell count can
cause anemia more easily. Low platelet count interferes with blood
coagulation when hemorrhaging from injuries.
Moreover, we must take into consideration that, if
there are any children with illnesses or disabilities currently living
in Fukushima Nakadori and Hamadori, this degree of effect on bone marrow
function might exacerbate their existing conditions.
Furthermore, this study underestimates the effect of
radiation exposure by using the control group in low contamination areas
as comparison. Therefor, we must be prepared to face much greater
health damage in reality
【Sections 3 & 4 summary】
- Fukushima Nakadori area continues to have radiation contamination comparable to highly contaminated areas in Chernobyl.
- Chernobyl epidemiological studies indicated that children who keep living in such areas have serious abnormalities in pulmonary function and bone marrow function.
- It is clear that an immediate evacuation from highly contaminated areas is imperative in order to prevent a possibility of irreversible health damages in children with future potential for life and improved health. This is the lesson we must all learn from the tragedy of Chernobyl.
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